A literature search of MEDLINE/PUBMED was conducted with the aim to highlight current endoscopic management of localised gastro-entero-pancreatic NETs. Relevant articles were identified through a manual search, and reference lists were reviewed for additional articles. The results of the research have been displayed in a narrative fashion to illustrate the actual state-of-the-art of endoscopic techniques in the treatment of NETs. Localised NETs of the stomach, duodenum and rectum can benefit from advanced endoscopic resection techniques (e.g., modified endoscopic mucosal resection, endoscopic full thickness resection, endoscopic submucosal dissection) according to centre expertise. Radiofrequency thermal ablation can be proposed as an alternative to surgery in selected patients with localised pancreatic NETs.
通过检索MEDLINE/PUBMED数据库,本文旨在阐述当前局限性胃肠胰神经内分泌肿瘤的内镜治疗进展。通过人工检索确定相关文献,并查阅参考文献以补充资料。研究结果以叙述性方式呈现,阐明当前神经内分泌肿瘤内镜治疗技术的最新进展。根据医疗中心的技术专长,胃、十二指肠及直肠的局限性神经内分泌肿瘤可采用改良内镜黏膜切除术、内镜全层切除术、内镜黏膜下剥离术等先进内镜切除技术进行治疗。对于特定局限性胰腺神经内分泌肿瘤患者,射频消融术可作为外科手术的替代治疗方案。