文章：

胃食管结合部腺癌的多学科综合治疗与外科管理策略

The Multidisciplinary Approach and Surgical Management of GE Junction Adenocarcinoma

原文发布日期：9 January 2024

DOI: 10.3390/cancers16020288

类型: Article

开放获取: 是

英文摘要：

Gastroesophageal (GE) junction adenocarcinoma is an aggressive malignancy of growing incidence and is associated with public health issues such as obesity and GERD. Management has evolved over the last two decades to incorporate a multidisciplinary approach, including endoscopic intervention, neoadjuvant chemotherapy/chemoradiation, and minimally invasive or more limited surgical approaches. Surgical approaches include esophagectomy, total gastrectomy, and, more recently, proximal gastrectomy. This review analyzes the evidence for and applicability of these varied approaches in management, as well as areas of continued controversy and investigation.

摘要翻译： 

胃食管结合部腺癌是一种发病率不断上升的侵袭性恶性肿瘤，其发生与肥胖及胃食管反流病等公共卫生问题密切相关。近二十年来，该疾病的诊疗模式已发展为包含内镜干预、新辅助化疗/放化疗及微创或局限性手术在内的多学科综合治疗体系。手术方式涵盖食管切除术、全胃切除术，以及近年来兴起的近端胃切除术。本文综述将系统分析上述不同治疗方案的循证依据与临床适用性，并探讨当前存在的争议领域及未来研究方向。

原文链接：

The Multidisciplinary Approach and Surgical Management of GE Junction Adenocarcinoma