Technological advances in radiation oncology are oriented towards improving treatment precision and tumor control. Among these advances, magnetic-resonance-image-guided radiation therapy (MRgRT) stands out, with technological advances to deliver targeted treatments adapted to a tumor’s anatomy on the day while minimizing incidental exposure to organs at risk, offering an unprecedented therapeutic advantage compared to X-ray-based IGRT delivery systems. This new technology changes the traditional workflow in radiation oncology and requires an evolution in team coordination to administer more precise treatments. Once implemented, it paves the way for newer indication for radiation therapy to safely deliver higher doses than ever before, with better preservation of healthy tissues to optimize patient outcomes. In this narrative review, we assess the technical aspects of the novel linear accelerators that can deliver MRgRT and summarize the available published experience to date, focusing on oncological results and future challenges.
放射肿瘤学的技术进步正朝着提高治疗精度和肿瘤控制的方向发展。其中,磁共振图像引导放射治疗(MRgRT)尤为突出,其技术进步能够根据当日的肿瘤解剖结构实施靶向治疗,同时最大限度地减少对危险器官的意外照射,与基于X射线的图像引导放射治疗系统相比,提供了前所未有的治疗优势。这项新技术改变了放射肿瘤学的传统工作流程,并要求团队协作的演进以实施更精准的治疗。一旦实施,它为放射治疗开辟了新的适应症,能够安全地提供比以往更高的剂量,同时更好地保护健康组织,以优化患者的治疗效果。在本叙述性综述中,我们评估了能够实施MRgRT的新型直线加速器的技术方面,并总结了迄今为止已发表的经验,重点关注肿瘤学结果和未来挑战。
MR-LINAC, a New Partner in Radiation Oncology: Current Landscape