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文章:

口腔鳞状细胞癌监测影像学的价值

The Value of Surveillance Imaging of Oral Squamous Cell Carcinoma

原文发布日期:1 January 2024

DOI: 10.3390/cancers16010207

类型: Article

开放获取: 是

 

英文摘要:

The evaluation of surveillance imaging of OSCC patients is a difficult task physicians have to face daily. Multiple patients experience a recurrence of this disease, which underlines the importance of regular patient monitoring programs. Our study analysed the value of surveillance imaging, such as computed tomography (CT) and nuclear magnetic resonance imaging (NMRI), as a patient monitoring programme and its effectiveness in achieving improvement in early recurrence detection. The study comprised 125 patients, out of which 56 (n= 56) showed radiological and 69 (n= 69) showed clinical and radiological conspicuous patterns in domestic follow-ups, respectively. The use of CT and NMRI showed a significant dependence on the histological result (p= 0.03). However, the different groups showed no significant dependence on the histological result (p= 0.96). The distribution of the histological biopsies, which were taken due to radiological changes, were prone to wrong positive diagnoses (false positives) in 71 percent. To conclude, imaging modalities should be chosen for each patient individually to reduce false positives, improve the early detection of recurrence, and increase the cure rate.

 

摘要翻译: 

口腔鳞状细胞癌患者的监测影像学评估是临床医生日常面临的一项艰巨任务。多数患者会出现疾病复发,这凸显了定期患者监测计划的重要性。本研究分析了计算机断层扫描和核磁共振成像等监测影像学作为患者监测方案的价值,及其在提高早期复发检出率方面的有效性。研究共纳入125例患者,其中56例在随访中仅显示影像学异常,69例同时存在临床与影像学异常表现。CT与NMRI的应用与组织学结果存在显著相关性(p=0.03),但不同异常表现组别与组织学结果无显著相关性(p=0.96)。因影像学改变而进行的组织活检中,71%存在假阳性诊断风险。综上所述,应针对患者个体化选择影像学检查方法,以降低假阳性率、提高复发早期检出率并提升治愈率。

 

原文链接:

The Value of Surveillance Imaging of Oral Squamous Cell Carcinoma

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