This population-based registry study aimed to report 30-day and one-year postoperative survival, five-year overall survival (OS), and disease-specific survival (DSS) among elderly (≥75 years old) colorectal cancer (CRC) patients. All new colorectal cancer cases from 2006–2015 were included and followed until death or the end of follow-up (end of 2016). Among 27,088 CRC patients, 11,306 patients were ≥75 years old. Among patients ≥ 75 years, 36.8% (n= 4160) had right-sided colon cancer, 21.9% (n= 2478) left-sided colon cancer, and 32.3% (n= 3650) rectal cancer. In this study population, 932 patients were aged ≥ 90. The 30-day postoperative OS for patients aged 75–79 was 96.1% (95% confidence interval [CI] 95.3–96.9) falling to 93.2% (95% CI 92.0–94.4) for patients aged 80–84. The one-year postoperative OS among patients aged 75–79 was 86.3% (95% CI 84.7–87.9) compared with 80.5% (95% CI 78.7–82.3) among patients aged 80–84. Five-year OS among patients aged 75–79 was 47.6% (95% CI 46.0–49.2) and 36.6% (95% CI 34.8–38.4) among patients aged 80–84, compared with 61.7% (95% CI 60.9–62.5) among younger patients (<75 years old). Survival among elderly CRC patients (≥75 years old) was in general fairly good when compared with younger patients, especially among patients aged 75–79 and 80–84 with localized or locally advanced disease.
这项基于人群的登记研究旨在报告老年（≥75岁）结直肠癌患者的术后30天及一年生存率、五年总生存率（OS）和疾病特异性生存率（DSS）。研究纳入了2006年至2015年所有新发结直肠癌病例，并随访至患者死亡或随访期结束（2016年底）。在27,088例结直肠癌患者中，有11,306例患者年龄≥75岁。在≥75岁的患者中，36.8%（n=4160）为右半结肠癌，21.9%（n=2478）为左半结肠癌，32.3%（n=3650）为直肠癌。研究人群中，932例患者年龄≥90岁。75-79岁患者的术后30天总生存率为96.1%（95%置信区间[CI] 95.3-96.9），而80-84岁患者则降至93.2%（95% CI 92.0-94.4）。75-79岁患者的术后一年总生存率为86.3%（95% CI 84.7-87.9），而80-84岁患者为80.5%（95% CI 78.7-82.3）。75-79岁患者的五年总生存率为47.6%（95% CI 46.0-49.2），80-84岁患者为36.6%（95% CI 34.8-38.4），而年轻患者（<75岁）的五年总生存率为61.7%（95% CI 60.9-62.5）。与年轻患者相比，老年结直肠癌患者（≥75岁）的生存状况总体良好，尤其是75-79岁和80-84岁且患有局部或局部进展期疾病的患者。
肿瘤(癌症)患者之家