文章：

口腔癌术中切缘评估：光谱学的潜在作用

Intraoperative Assessment of Resection Margin in Oral Cancer: The Potential Role of Spectroscopy

原文发布日期：26 December 2023

DOI: 10.3390/cancers16010121

类型: Article

开放获取: 是

英文摘要：

In parallel with the increasing number of oncological cases, the need for faster and more efficient diagnostic tools has also appeared. Different diagnostic approaches are available, such as radiological imaging or histological staining methods, but these do not provide adequate information regarding the resection margin, intraoperatively, or are time consuming. The purpose of this review is to summarize the current knowledge on spectrometric diagnostic modalities suitable for intraoperative use, with an emphasis on their relevance in the management of oral cancer. The literature agrees on the sensitivity, specificity, and accuracy of spectrometric diagnostic modalities, but further long-term prospective, multicentric clinical studies are needed, which may standardize the intraoperative assessment of the resection margin and the use of real-time spectroscopic approaches.

摘要翻译： 

随着肿瘤病例数量的增加，对更快速、更高效诊断工具的需求也随之出现。目前存在多种诊断方法，如放射影像学或组织学染色技术，但这些方法在术中无法提供关于切除边缘的充分信息，或耗时较长。本综述旨在总结当前适用于术中使用的光谱诊断方法的相关知识，并重点探讨其在口腔癌治疗中的应用价值。现有文献普遍认可光谱诊断方法的敏感性、特异性和准确性，但仍需开展进一步长期前瞻性、多中心临床研究，以规范术中切除边缘的评估及实时光谱技术的应用。

原文链接：

Intraoperative Assessment of Resection Margin in Oral Cancer: The Potential Role of Spectroscopy