文章：

大自然的绿色潜能：大戟科植物的抗癌特性

Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family

原文发布日期：25 December 2023

DOI: 10.3390/cancers16010114

类型: Article

开放获取: 是

英文摘要：

The number of cancer cases will reach 24 million in 2040, according to the International Agency for Research on Cancer. Current treatments for cancer are not effective and selective for most patients; for this reason, new anticancer drugs need to be developed and researched enough. There are potentially useful drugs for cancer isolated from plants that are being used in the clinic. Available information about phytochemistry, traditional uses, in vitro and in vivo experiments with plants, and pure compounds isolated from the Euphorbiaceae family indicates that this family of plants has the potential to develop anticancer drugs. This review examines selected species from the Euphorbiaceae family and their bioactive compounds that could have potential against different types of cancer cells. It reviews the activity of crude extracts, isolated compounds, and nanoparticles and the potential underlying mechanisms of action.

摘要翻译： 

根据国际癌症研究机构预测，2040年全球癌症病例数将达到2400万例。当前癌症治疗方案对多数患者缺乏足够疗效与选择性，因此亟需开发并深入研究新型抗癌药物。从植物中分离的潜在有效抗癌成分已在临床得到应用。关于大戟科植物的植物化学特性、传统用途、体外与体内实验数据以及从中分离的纯化合物信息表明，该科植物具有开发抗癌药物的潜力。本综述系统考察了大戟科特定物种及其生物活性成分对不同类型癌细胞的潜在抑制作用，重点评述了粗提物、分离化合物及纳米颗粒的活性表现，并探讨了其潜在作用机制。

原文链接：

Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family