We aimed to improve the available information on morphology and stage for cutaneous melanoma in the population-based cancer registry of the Bucaramanga Metropolitan Area in Colombia. The incidence and survival rates and the distribution of melanoma patients by age, gender, anatomical subsite, and histological subtype were calculated. All 113 melanoma patients (median age 61) were followed up (median time 7.4 years). This exercise (filling in missing information in the registry by manual search of patient clinical record and other available information) yielded more identified invasive melanomas and cases with complete information on anatomical localization and stage. Age-standardized incidence and mortality rates were 1.86 and 1.08, being slightly higher for males. Most melanomas were localized on the lower limbs, followed by the trunk. For 35% of all melanomas, the morphological subtype remained unknown. Most of the remaining melanomas were nodular and acral lentiginous melanomas. Overall global and relative 5-year survival was 61.6% and 71.3%, respectively, with poorer survival for males than females. Melanomas on the head and neck and unspecified anatomical sites had the worst survival. Patients without stage information in their medical files had excellent survival, unlike patients for whom medical files were no longer available. This study shows the possibility of improving data availability and the importance of good quality population-based data.
本研究旨在完善哥伦比亚布卡拉曼加都市区基于人群的癌症登记系统中皮肤黑色素瘤的形态学与分期信息。通过计算发病率、生存率，并按年龄、性别、解剖亚部位及组织学亚型对黑色素瘤患者进行分布分析，对全部113例黑色素瘤患者（中位年龄61岁）进行了随访（中位随访时间7.4年）。通过人工检索患者临床记录及其他可用信息以填补登记系统缺失数据的实践，显著增加了可识别的浸润性黑色素瘤数量，并提高了解剖定位与分期信息的完整性。年龄标准化发病率和死亡率分别为1.86和1.08，男性略高于女性。黑色素瘤好发于下肢，其次为躯干。35%的病例组织学亚型未明确，在已明确亚型的病例中以结节性黑色素瘤和肢端雀斑样痣黑色素瘤为主。总体五年观察生存率和相对生存率分别为61.6%和71.3%，男性生存率低于女性。头颈部及解剖部位不明的黑色素瘤预后最差。医疗档案中缺乏分期信息的患者生存状况良好，而档案缺失的患者则不然。本研究证实了提升数据可获得性的可行性，并凸显了高质量人群数据的重要性。
肿瘤(癌症)患者之家