With better survival rates for patients diagnosed with cancer, more attention has been focused on future risks, like fertility decline due to gonadotoxic treatment. In this regard, the emphasis during counselling regarding possible preservation options is often on the treatment itself, meaning that the medical and emotional needs of patients regarding counselling, treatment, and future fertility are often overlooked. This review focuses on patient-reported outcomes (PROs) and patient experiences regarding fertility preservation (FP)—among adolescents and young adults (AYAs) with cancer. A systematic review of the literature, with a systematic search of online databases, was performed, resulting in 61 selected articles. A quality assessment was performed by a mixed methods appraisal tool (MMAT). Based on this search, three important topics emerged: initiating discussion about the risk of fertility decline, acknowledging the importance of future fertility, and recognizing the need for more verbal and written patient-specific information. In addition, patients value follow-up care and the opportunity to rediscuss FP and their concerns about future fertility and use of stored material. A clear FP healthcare pathway can prevent delays in receiving a referral to a fertility specialist to discuss FP options and initiating FP treatment. This patient-centered approach will optimize FP experiences and help to establish a process to achieve long-term follow up after FP treatment.
随着癌症患者生存率的提高，人们越来越关注治疗带来的远期风险，例如性腺毒性治疗导致的生育能力下降。当前关于生育力保存方案的咨询往往侧重于治疗本身，这意味着患者在咨询、治疗及未来生育方面的医疗需求和情感需求常被忽视。本综述聚焦于青少年及年轻成人癌症患者对生育力保存的患者报告结局及体验。通过对在线数据库进行系统性文献检索，共纳入61篇相关文献，并采用混合方法评估工具进行质量评价。基于文献分析，我们总结出三个关键议题：启动生育力下降风险的讨论、确认未来生育意愿的重要性、以及认识患者个体化口头与书面信息的必要性。此外，患者重视后续随访护理，并希望有机会重新讨论生育力保存方案，以及对未来生育能力和保存材料使用的担忧。建立清晰的生育力保存医疗路径，可避免转诊至生育专家讨论保存方案及启动保存治疗的延迟。这种以患者为中心的方法将优化生育力保存体验，并有助于建立保存治疗后的长期随访机制。
肿瘤(癌症)患者之家