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文章:

晚期卵巢癌腹膜癌病影像学评估:CT、MRI、放射组学特征与可切除性标准

Imaging of Peritoneal Carcinomatosis in Advanced Ovarian Cancer: CT, MRI, Radiomic Features and Resectability Criteria

原文发布日期:13 December 2023

DOI: 10.3390/cancers15245827

类型: Article

开放获取: 是

 

英文摘要:

PC represents the most striking picture of the loco-regional spread of ovarian cancer, configuring stage III. In the last few years, many papers have evaluated the role of imaging and therapeutic management in patients with ovarian cancer and PC. This paper summed up the literature on traditional approaches to the imaging of peritoneal carcinomatosis in advanced ovarian cancer, presenting classification systems, most frequent patterns, routes of spread and sites that are difficult to identify. The role of imaging in diagnosis was investigated, with particular attention to the reported sensitivity and specificity data—computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography-CT (PET-CT)—and to the peritoneal cancer index (PCI). In addition, we explored the therapeutic possibilities and radiomics applications that can impact management of patients with ovarian cancer. Careful staging is mandatory, and patient selection is one of the most important factors influencing complete cytoreduction (CCR) outcome: an accurate pre-operative imaging may allow selection of patients that may benefit most from primary cytoreductive surgery.

 

摘要翻译: 

腹膜癌病是卵巢癌局部区域扩散最显著的表现,构成III期疾病。近年来,多项研究评估了影像学检查与治疗管理在卵巢癌及腹膜癌病患者中的作用。本文综述了晚期卵巢癌腹膜癌病影像学传统方法的文献,系统阐述了其分类体系、常见播散模式、转移途径及难以识别的病灶部位。研究探讨了影像学在诊断中的作用,重点关注计算机断层扫描(CT)、磁共振成像(MRI)、正电子发射断层扫描-CT(PET-CT)等技术的敏感性与特异性数据,以及腹膜癌指数(PCI)的应用价值。此外,我们还深入分析了影响卵巢癌患者管理的治疗可能性及影像组学应用。精确分期至关重要,患者选择是影响肿瘤细胞减灭术完全切除效果的关键因素:精准的术前影像评估有助于筛选最能从初次肿瘤细胞减灭术中获益的患者群体。

 

原文链接:

Imaging of Peritoneal Carcinomatosis in Advanced Ovarian Cancer: CT, MRI, Radiomic Features and Resectability Criteria

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