Cardio-oncology currently faces one of the greatest challenges in the field of health care. The main goal of this discipline is to ensure that patients treated for cancer do not suffer or die from cardiovascular disease. The number of studies on the mechanisms of heart injury during cancer treatment is constantly increasing. However, there is insufficient data on heart rhythm disorders that may result from this treatment. This issue seems to be particularly important in patients with lung cancer, in whom anticancer therapy, especially radiotherapy, may contribute to the onset of cardiac arrhythmias. The observed relationship between cardiac dosimetry and radiotherapy-induced cardiotoxicity in lung cancer treatment may explain the increased mortality from cardiovascular causes in patients after chest irradiation. Further research is essential to elucidate the role of cardiac arrhythmias in this context. Conversely, recent reports have highlighted the application of stereotactic arrhythmia radioablation (STAR) in the treatment of ventricular tachycardia. This review of available studies on the epidemiology, pathogenesis, diagnosis, and treatment of arrhythmias in patients treated for lung cancer aims to draw attention to the need for regular cardiological monitoring in this group of patients. Improving cardiac care for patients with lung cancer has the potential to enhance their overall therapeutic outcomes.
心脏肿瘤学目前正面临医疗保健领域最严峻的挑战之一。该学科的主要目标是确保接受癌症治疗的患者不因心血管疾病而遭受痛苦或死亡。关于癌症治疗期间心脏损伤机制的研究数量持续增长，但关于治疗可能引发的心律失常数据仍显不足。这一问题在肺癌患者中尤为突出，其抗癌治疗（特别是放射治疗）可能诱发心律失常。在肺癌治疗中观察到的心脏剂量测定与放疗诱发心脏毒性之间的关联，或许能解释胸部放疗后患者心血管原因死亡率升高的现象。进一步研究对于阐明心律失常在此背景下的作用至关重要。反观近年研究，立体定向心律失常放射消融术在室性心动过速治疗中的应用已引起学界关注。本文通过综述现有关于肺癌患者心律失常流行病学、发病机制、诊断及治疗的研究，旨在强调对该患者群体进行定期心脏监测的必要性。改善肺癌患者的心脏照护，有望提升其整体治疗效果。
Cardiac Arrhythmias in Patients Treated for Lung Cancer: A Review
肿瘤(癌症)患者之家