Tuberculum sellae meningioma (TSM) is a challenging tumor that grows close to several crucial structures, such as the optic nerve, arteries, and pituitary. Surgical treatment is currently evolving from a transcranial microsurgical resection to a transsphenoidal approach. This study examined the clinical profile of patients with tuberculum sellae meningioma and explored its relationship with scoring systems. This retrospective observational study included patients with TSM who underwent surgery at the Department of Neurosurgery at our hospital between 2017 and 2022. The patients were excluded if their data required completion. The clinical profiles of the patients were counted and transformed into a scoring system using several variables such as size, vascular, and canal invasion. We then analyzed the relationship between the clinical signs and symptoms to determine the efficacy of this scoring system. Thirty-six patients were included in the study. Most of our patients had a high score for tumor diameter, bilateral canal invasion, and vascular invasion (2-2-2). Moreover, when related to clinical signs, there was no relationship between the canal and vascular invasion and decreased visual acuity. Tuberculum sellae meningioma mostly causes visual impairment and several other symptoms, such as hemianopsia and parasellar extension. Several factors in the scoring system should also be considered to predict outcomes, such as the onset of visual symptoms, peritumoral edema, and grade of excision.
鞍结节脑膜瘤是一种具有挑战性的肿瘤，其生长位置邻近视神经、动脉及垂体等多个关键结构。目前手术治疗正从经颅显微外科切除向经蝶入路演变。本研究旨在分析鞍结节脑膜瘤患者的临床特征，并探讨其与评分系统的关联性。这项回顾性观察研究纳入了2017年至2022年间在我院神经外科接受手术的鞍结节脑膜瘤患者，排除数据不完整的病例。通过肿瘤大小、血管侵犯及视神经管侵犯等多个变量对患者临床特征进行统计并转化为评分系统，进而分析临床症状与评分系统的关联以评估该评分体系的有效性。研究共纳入36例患者，多数患者在肿瘤直径、双侧视神经管侵犯及血管侵犯方面呈现高分值特征（2-2-2）。进一步分析显示，视神经管侵犯和血管侵犯与视力下降无显著相关性。鞍结节脑膜瘤主要导致视力损害及偏盲、鞍旁侵犯等其他症状。在预测预后时，需综合考虑评分系统中视觉症状出现时间、瘤周水肿程度及切除分级等多重因素。
肿瘤(癌症)患者之家