文章：

肝脏热消融区域的计算模型构建：一项系统性综述

Computational Modeling of Thermal Ablation Zones in the Liver: A Systematic Review

原文发布日期：1 December 2023

DOI: 10.3390/cancers15235684

类型: Article

开放获取: 是

英文摘要：

Purpose: This systematic review aims to identify, evaluate, and summarize the findings of the literature on existing computational models for radiofrequency and microwave thermal liver ablation planning and compare their accuracy. Methods: A systematic literature search was performed in the MEDLINE and Web of Science databases. Characteristics of the computational model and validation method of the included articles were retrieved. Results: The literature search identified 780 articles, of which 35 were included. A total of 19 articles focused on simulating radiofrequency ablation (RFA) zones, and 16 focused on microwave ablation (MWA) zones. Out of the 16 articles simulating MWA, only 2 used in vivo experiments to validate their simulations. Out of the 19 articles simulating RFA, 10 articles used in vivo validation. Dice similarity coefficients describing the overlap between in vivo experiments and simulated RFA zones varied between 0.418 and 0.728, with mean surface deviations varying between 1.1 mm and 8.67 mm. Conclusion: Computational models to simulate ablation zones of MWA and RFA show considerable heterogeneity in model type and validation methods. It is currently unknown which model is most accurate and best suitable for use in clinical practice.

摘要翻译： 

目的：本系统综述旨在识别、评估并总结现有关于射频与微波热消融肝脏治疗规划的计算模型文献，并比较其准确性。 方法：在MEDLINE和Web of Science数据库中进行系统性文献检索。提取纳入文献中计算模型的特征及验证方法。 结果：文献检索共识别出780篇文章，其中35篇符合纳入标准。共有19篇文章聚焦于模拟射频消融（RFA）区域，16篇聚焦于微波消融（MWA）区域。在模拟MWA的16篇文章中，仅2篇采用体内实验验证其模拟结果；而在模拟RFA的19篇文章中，有10篇采用了体内验证。描述体内实验与模拟RFA区域重叠度的Dice相似系数介于0.418至0.728之间，平均表面偏差范围为1.1毫米至8.67毫米。 结论：模拟MWA和RFA消融区域的计算模型在模型类型和验证方法上存在显著异质性。目前尚不清楚哪种模型最为准确且最适合临床应用。

原文链接：

Computational Modeling of Thermal Ablation Zones in the Liver: A Systematic Review