Patients with lung cancer may experience deterioration in quality of life due to adverse effects caused by their disease and its treatment. Although exercise programs have been shown to improve quality of life in certain stages of the disease, the overall impact on this population is unknown. The objective of this research was to evaluate the effect of physical activity on the self-perception of quality of life, physical wellbeing and dyspnea in lung cancer patients. Thirteen articles were included. Five meta-analyses were performed using the standardized mean difference (SMD) with 95% confidence intervals (CI) to evaluate the target outcomes. Results showed significant differences in quality of life (p= 0.01; SMD = 0.43, 95% CI = 0.10, 0.75), physical functioning (p= 0.01; SMD = 0.27, 95% CI = 0.06, 0.49) and physical wellbeing (p= 0.01; SMD = 0.37, 95% CI = 0.08, 0.67) in favour of participants who have undergone the programme compared to those who have not, without significant differences between the two groups in dyspnea. This study shows how physical activity interventions could have positive effects on physical functioning and physical wellbeing but could also be effective for improving quality of life in patients with lung cancer.
肺癌患者可能因疾病及其治疗所引发的不良反应而导致生活质量下降。尽管已有研究表明运动干预在疾病特定阶段能够改善生活质量，但其对该人群的整体影响尚不明确。本研究旨在评估体力活动对肺癌患者生活质量自我感知、躯体健康及呼吸困难的影响。共纳入13篇文献，采用标准化均数差（SMD）及95%置信区间（CI）对目标结局指标进行五项荟萃分析。结果显示：与未参与运动干预的患者相比，参与运动计划的患者在生活质量（p=0.01；SMD=0.43，95% CI=0.10-0.75）、躯体功能（p=0.01；SMD=0.27，95% CI=0.06-0.49）及躯体健康（p=0.01；SMD=0.37，95% CI=0.08-0.67）方面均呈现显著改善，而两组间呼吸困难程度未见显著差异。本研究表明，体力活动干预不仅可能对肺癌患者的躯体功能和躯体健康产生积极影响，还可能有效改善其整体生活质量。
肿瘤(癌症)患者之家