Cancer is the second leading cause of death. It is thus essential to examine cancer trends in all regions. In addition, trend data after 2019 and on cancer 1-year mortality are scarce. Our aim was to analyze incidence and 1-year mortality cancer trends in northeastern Spain during 2005–2020. We used the Osona Tumor Registry, which registers cancer incidence and mortality in Osona. The mortality information came from the Spanish Death Index. We analyzed age-standardized incidence rates and 1-year mortality by sex in the population aged > 17 years during 2005–2020. Trends were examined with negative binomial and joinpoint regression. Incidence rates of colorectal, lung and bronchus, and urinary bladder cancer increased annually in females by 2.86%, 4.20%, and 4.56%, respectively. In males, the incidence of stomach and prostate cancer decreased annually by 3.66% and 2.05%, respectively. One-year mortality trends decreased annually for endometrium cancer (−9.0%) and for colorectal cancer in males (−3.1%). From 2019 to 2020, the incidence of cancer decreased, while 1-year mortality increased in both sexes. In a North-Eastern Spanish county, 1-year mortality decreased for endometrium cancer in females and for colorectal cancer in males. Our results suggest a trend of decreasing cancer incidence and increasing cancer mortality as a result of the COVID-19 pandemic.
癌症是第二大死亡原因，因此分析各地区的癌症趋势至关重要。此外，2019年后的趋势数据及癌症一年期死亡率数据较为缺乏。本研究旨在分析2005年至2020年西班牙东北部地区癌症发病率与一年期死亡率的变化趋势。数据来源于奥索纳肿瘤登记处（该机构系统记录奥索纳地区的癌症发病与死亡情况），死亡信息则来自西班牙死亡指数数据库。我们针对17岁以上人群，分析了2005-2020年间按性别划分的年龄标准化发病率及一年期死亡率，并采用负二项回归和连接点回归进行趋势检验。 结果显示，女性结直肠癌、肺癌与支气管癌、膀胱癌的发病率年均增长率分别为2.86%、4.20%和4.56%；男性胃癌和前列腺癌发病率则年均下降3.66%和2.05%。在一年期死亡率方面，女性子宫内膜癌（-9.0%）和男性结直肠癌（-3.1%）呈现年均下降趋势。值得注意的是，2019年至2020年间，两性癌症发病率均出现下降，而一年期死亡率则同步上升。 在西班牙东北部某县的研究表明，女性子宫内膜癌和男性结直肠癌的一年期死亡率呈下降态势。我们的研究结果提示，COVID-19大流行可能导致癌症发病率下降和死亡率上升的趋势变化。
Trend and Joinpoint Analysis of Cancer Incidence and 1-Year Mortality in North-East Spain 2005–2020
肿瘤(癌症)患者之家