文章：

靶向治疗在晚期胃癌中应用的临床视角

A Clinical Viewpoint on the Use of Targeted Therapy in Advanced Gastric Cancer

原文发布日期：20 November 2023

DOI: 10.3390/cancers15225490

类型: Article

开放获取: 是

英文摘要：

The development of therapies for advanced gastric cancer (GC) has made significant progress over the past few years. The identification of new molecules and molecular targets is expanding our understanding of the disease’s intricate nature. The end of the classical oncology era, which relied on well-studied chemotherapeutic agents, is giving rise to novel and unexplored challenges, which will cause a significant transformation of the current oncological knowledge in the next few years. The integration of established clinically effective regimens in additional studies will be crucial in managing these innovative aspects of GC. This study aims to present an in-depth and comprehensive review of the clinical advancements in targeted therapy and immunotherapy for advanced GC.

摘要翻译： 

近年来，晚期胃癌治疗领域取得了显著进展。新型分子及分子靶点的发现不断深化我们对疾病复杂本质的认知。随着依赖经典化疗药物的传统肿瘤学时代逐渐终结，一系列前所未有的新挑战正在涌现，这将在未来几年引发肿瘤学认知体系的重大变革。在后续研究中整合经临床验证的有效治疗方案，将成为把握胃癌治疗创新方向的关键。本研究旨在系统综述晚期胃癌靶向治疗与免疫治疗的临床进展，提供全面深入的学术视角。

原文链接：

A Clinical Viewpoint on the Use of Targeted Therapy in Advanced Gastric Cancer