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文章:

癌症相关性腹部静脉血栓形成

Cancer-Associated Abdominal Vein Thrombosis

原文发布日期:4 November 2023

DOI: 10.3390/cancers15215293

类型: Article

开放获取: 是

 

英文摘要:

Cancer is associated with an increased risk of developing venous thromboembolism, due to its direct influence on the three pillars of Virchow’s triad (e.g., compression on the blood vessels by the tumour, blood vessels invasion, and cytokine release), together with the effect of exogenous factors (such as chemotherapy, radiotherapy, surgery). In cancer patients, the risk of thrombosis at unusual sites, such as splanchnic, ovarian and renal vein thrombosis, is also increased. Abdominal vein thromboses are frequently incidental findings on abdominal imaging performed as part of the diagnostic/staging workup or the follow-up care of malignancies. There is little evidence on the management of unusual site venous thromboembolism in cancer patients since there are only a few specific recommendations; thus, the management follows the general principles of the treatment of cancer-associated deep vein thrombosis and pulmonary embolism. This narrative review summarises the latest evidence on cancer-associated abdominal vein thrombosis, i.e., thrombosis of the splanchnic, ovarian and renal veins.

 

摘要翻译: 

癌症因其对Virchow三要素(如肿瘤对血管的压迫、血管侵犯及细胞因子释放)的直接影响,加之外源性因素(如化疗、放疗、手术)的作用,导致静脉血栓栓塞风险显著增加。在癌症患者中,非典型部位(如内脏静脉、卵巢静脉及肾静脉)的血栓形成风险亦随之上升。腹部静脉血栓常作为恶性肿瘤诊断分期或随访期间腹部影像学检查的偶然发现。目前关于癌症患者非典型部位静脉血栓栓塞管理的证据有限,仅存少量具体建议,因此其治疗遵循癌症相关深静脉血栓和肺栓塞的一般原则。本叙述性综述总结了癌症相关腹部静脉血栓(即内脏静脉、卵巢静脉及肾静脉血栓)的最新证据。

 

原文链接:

Cancer-Associated Abdominal Vein Thrombosis

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