文章：

定义MRI在结直肠与神经内分泌肝转移诊断中相对于CT的优越性

Defining MRI Superiority over CT for Colorectal and Neuroendocrine Liver Metastases

原文发布日期：23 October 2023

DOI: 10.3390/cancers15205109

类型: Article

开放获取: 是

英文摘要：

Background: We compared CT and MRI for staging metastatic colorectal or neuroendocrine liver metastases (CRLMs and NELMs, respectively) to assess their impact on tumor burden. Methods: A prospectively maintained database was queried for patients who underwent both imaging modalities within 3 months, with two blinded radiologists (R1 and R2) independently assessing the images for liver lesions. To minimize recall bias, studies were grouped by modality, and were randomized and evaluated separately. Results: Our query yielded 76 patients (42 CRLMs; 34 NELMs) with low interrater variability (intraclass correlation coefficients: CT = 0.941, MRI = 0.975). For CRLMs, there were no significant differences in lesion number or size between CT and MRI. However, in NELMs, Eovist®-enhanced MRI detected more lesions (R1: 14.3 vs. 12.1,p= 0.02; R2: 14.4 vs. 12.4,p= 0.01) and smaller lesions (R1: 5.7 vs. 4.4,p= 0.03; R2: 4.8 vs. 2.9,p= 0.02) than CT. Conclusions: CT and MRI are equivalent for CRLMs, but for NELMs, MRI outperforms CT in detecting more and smaller lesions, potentially influencing treatment planning and surgery.

摘要翻译： 

背景：本研究比较了CT与MRI在评估结直肠癌肝转移（CRLMs）和神经内分泌肿瘤肝转移（NELMs）肿瘤负荷中的分期效能。方法：通过检索前瞻性维护的数据库，纳入3个月内同时接受两种影像学检查的患者，由两位盲态放射科医师（R1和R2）独立评估肝脏病灶。为减少回忆偏倚，按检查方式分组后随机排序并分别评估。结果：共纳入76例患者（42例CRLMs；34例NELMs），评估者间一致性较高（组内相关系数：CT=0.941，MRI=0.975）。对于CRLMs，CT与MRI在病灶数量和大小方面无显著差异。然而对于NELMs，Eovist®增强MRI较CT检测到更多病灶（R1：14.3 vs. 12.1，p=0.02；R2：14.4 vs. 12.4，p=0.01）及更小病灶（R1：5.7 vs. 4.4，p=0.03；R2：4.8 vs. 2.9，p=0.02）。结论：CT与MRI对CRLMs评估效能相当，但对NELMs而言，MRI在检测更多、更小病灶方面优于CT，可能影响治疗决策与手术规划。

原文链接：

Defining MRI Superiority over CT for Colorectal and Neuroendocrine Liver Metastases