文章：

IA期宫颈癌保守治疗病例分析

A Case for the Conservative Management of Stage IA Cervical Cancer

原文发布日期：19 October 2023

DOI: 10.3390/cancers15205051

类型: Article

开放获取: 是

英文摘要：

Cervical cancer remains a significant public health concern within the United States and across the world. Cervical cancer is most frequently diagnosed in women between the ages of 35 and 44 and therefore affects a younger patient population than many other cancers. The management of early-stage disease has frequently utilized radical hysterectomy with the associated increased surgical morbidity, without clear evidence of any benefits. In stage IA disease, there are retrospective pathologic data supporting the safety of conservative surgery and lymphadenectomy over radical hysterectomy. There are also emerging prospective studies supporting conservative management. This editorial presents the evidence for conservative management of stage IA cervical cancer by reviewing the existing retrospective studies as well as the ongoing prospective studies.

摘要翻译： 

宫颈癌在美国乃至全球范围内仍是一个重大的公共卫生问题。该疾病最常确诊于35至44岁女性群体，因此相较于其他多种癌症，其影响的患者人群更为年轻。早期宫颈癌的治疗常采用根治性子宫切除术，但该术式伴随手术并发症风险增加，且缺乏明确证据表明其具有显著优势。对于IA期宫颈癌，现有回顾性病理学数据支持保守性手术联合淋巴结清扫术的安全性优于根治性子宫切除术。同时，新兴的前瞻性研究也为保守治疗提供了进一步支持。本述评通过梳理现有回顾性研究及进行中的前瞻性研究，系统论证了IA期宫颈癌保守治疗的循证依据。

原文链接：

A Case for the Conservative Management of Stage IA Cervical Cancer