Oral cancer poses a major health challenge in Taiwan, consistently ranking among the highest globally in both incidence and cancer-related mortality. Transoral robotic surgery (TORS) has potential advantages over open surgery, but its long-term oncologic outcomes are not well established. In this study, we sought to elucidate the role of TORS in improving treatment outcomes among oral cancer patients. A case–control study with propensity score matching was conducted in a single teaching hospital in Taiwan. It included 72 oral cancer patients in each group to analyze and compare survival outcomes between the surgical approaches. The TORS group demonstrated a higher negative resection margin rate, a lower mortality risk and better overall survival than the open-surgery group. Multivariate Cox regression analysis confirmed TORS’s association with a reduced risk of death. Kaplan–Meier survival analysis and log-rank tests indicated significantly better survival outcomes for the TORS group across all cancer stages. Moreover, the TORS group exhibited improved overall survival rates for stage III and IV patients compared to the conventional open-surgery group. In conclusion, this study suggests that TORS may offer better overall survival rates and potential advantages over conventional surgery for oral cancer treatment.
口腔癌在台湾构成重大健康挑战，其发病率和癌症相关死亡率长期位居全球前列。经口机器人手术相较于传统开放手术具有潜在优势，但其长期肿瘤学疗效尚未明确。本研究旨在阐明经口机器人手术对改善口腔癌患者治疗结局的作用。我们在台湾某教学医院开展了一项倾向评分匹配的病例对照研究，每组纳入72例口腔癌患者，以分析和比较不同手术方式的生存结局。结果显示，与开放手术组相比，经口机器人手术组具有更高的阴性切缘率、更低的死亡风险及更好的总生存期。多变量Cox回归分析证实经口机器人手术与死亡风险降低相关。Kaplan-Meier生存分析和时序检验表明，经口机器人手术组在所有癌症分期中均表现出显著更优的生存结局。此外，对于III期和IV期患者，经口机器人手术组较传统开放手术组显示出更高的总生存率。综上所述，本研究提示经口机器人手术可能为口腔癌治疗提供更优的总生存率，并较传统手术具有潜在优势。
肿瘤(癌症)患者之家