Advancements in intraoperative visualization and imaging techniques are increasingly central to the success and safety of brain tumor surgery, leading to transformative improvements in patient outcomes. This comprehensive review intricately describes the evolution of conventional and emerging technologies for intraoperative imaging, encompassing the surgical microscope, exoscope, Raman spectroscopy, confocal microscopy, fluorescence-guided surgery, intraoperative ultrasound, magnetic resonance imaging, and computed tomography. We detail how each of these imaging modalities contributes uniquely to the precision, safety, and efficacy of neurosurgical procedures. Despite their substantial benefits, these technologies share common challenges, including difficulties in image interpretation and steep learning curves. Looking forward, innovations in this field are poised to incorporate artificial intelligence, integrated multimodal imaging approaches, and augmented and virtual reality technologies. This rapidly evolving landscape represents fertile ground for future research and technological development, aiming to further elevate surgical precision, safety, and, most critically, patient outcomes in the management of brain tumors.
术中可视化与成像技术的进步日益成为脑肿瘤手术成功与安全的核心,显著改善了患者预后。本综述系统阐述了术中成像技术从传统到新兴的发展历程,涵盖手术显微镜、外视镜、拉曼光谱、共聚焦显微镜、荧光引导手术、术中超声、磁共振成像及计算机断层扫描等多种技术。我们详细分析了每种成像模式如何独特地提升神经外科手术的精确性、安全性和有效性。尽管这些技术具有显著优势,但仍面临图像解读困难和学习曲线陡峭等共同挑战。展望未来,该领域创新将融合人工智能、多模态集成成像以及增强与虚拟现实技术。这一快速发展的领域为未来研究和技术突破提供了广阔空间,旨在进一步提升脑肿瘤治疗中的手术精准度、安全性,并最终改善患者预后。