文章：

内镜下治疗巴雷特食管异型增生及早期食管腺癌

Endoscopic Management of Dysplastic Barrett’s Oesophagus and Early Oesophageal Adenocarcinoma

原文发布日期：28 September 2023

DOI: 10.3390/cancers15194776

类型: Article

开放获取: 是

英文摘要：

Barrett’s oesophagus is a pathological condition whereby the normal oesophageal squamous mucosa is replaced by specialised, intestinal-type metaplasia, which is strongly linked to chronic gastro-oesophageal reflux. A correct endoscopic and histological diagnosis is pivotal in the management of Barrett’s oesophagus to identify patients who are at high risk of progression to neoplasia. The presence and grade of dysplasia and the characteristics of visible lesions within the mucosa of Barrett’s oesophagus are both important to guide the most appropriate endoscopic therapy. In this review, we provide an overview on the management of Barrett’s oesophagus, with a particular focus on recent advances in the diagnosis and recommendations for endoscopic therapy to reduce the risk of developing oesophageal adenocarcinoma.

摘要翻译： 

巴雷特食管是一种病理状态，其特征是正常的食管鳞状上皮被特化的肠型化生上皮所取代，该病变与慢性胃食管反流密切相关。准确的内镜及组织学诊断对于巴雷特食管的管理至关重要，有助于识别进展为肿瘤高风险的患者。化生的存在与否及其分级，以及巴雷特食管黏膜内可见病变的特征，对于指导最适宜的内镜治疗均具有重要意义。本文综述了巴雷特食管的管理策略，重点聚焦于诊断方面的最新进展以及内镜治疗建议，以降低发展为食管腺癌的风险。

原文链接：

Endoscopic Management of Dysplastic Barrett’s Oesophagus and Early Oesophageal Adenocarcinoma