文章：

内镜超声引导下局部区域治疗在实体胰腺肿瘤中的应用

Endoscopic Ultrasound-Guided Locoregional Treatments for Solid Pancreatic Neoplasms

原文发布日期：25 September 2023

DOI: 10.3390/cancers15194718

类型: Article

开放获取: 是

英文摘要：

Solid pancreatic neoplasms are one of the most diagnosed gastrointestinal malignancies thanks to the current and progressive advances in radiologic methods. Endoscopic ultrasound-guided techniques have over time gained a prominent role in the differential diagnosis and characterization of these pancreatic lesions, including pancreatic cancer, neuroendocrine tumors, and metastases. Recently, several endoscopic ultrasound-guided locoregional treatment techniques, which are divided into thermal ablative techniques and non-thermal injection techniques, have been developed and applied in different settings for the treatment of solid pancreatic neoplasms. The most common ablative techniques are radiofrequency, microwave, laser, photodynamic therapy and hybrid techniques such as hybrid cryothermal ablation. The most common injection techniques are ethanol injection, immunotherapy and brachytherapy. In this review, we update evidence about the efficacy and safety of endoscopic ultrasound-guided locoregional treatments for solid pancreatic neoplasms.

摘要翻译： 

随着放射学方法的不断进步，实性胰腺肿瘤已成为诊断率最高的胃肠道恶性肿瘤之一。内镜超声引导技术已在胰腺病变（包括胰腺癌、神经内分泌肿瘤及转移瘤）的鉴别诊断与特征分析中占据重要地位。近年来，多种内镜超声引导下的局部治疗技术被开发并应用于实性胰腺肿瘤的治疗，这些技术主要分为热消融技术和非热注射技术两大类。最常见的消融技术包括射频消融、微波消融、激光消融、光动力疗法以及混合技术（如混合冷冻消融）。最常见的注射技术则包括乙醇注射、免疫治疗和近距离放射治疗。本文综述了内镜超声引导下局部治疗实性胰腺肿瘤的有效性和安全性的最新证据。

原文链接：

Endoscopic Ultrasound-Guided Locoregional Treatments for Solid Pancreatic Neoplasms