文章：

运用单案例实验设计与患者报告结局指标评估临床实践中癌症相关认知障碍的治疗效果

Using Single-Case Experimental Design and Patient-Reported Outcome Measures to Evaluate the Treatment of Cancer-Related Cognitive Impairment in Clinical Practice

原文发布日期：20 September 2023

DOI: 10.3390/cancers15184643

类型: Article

开放获取: 是

英文摘要：

Cancer-related cognitive impairment (CRCI) affects a large proportion of cancer survivors and has significant negative effects on survivor function and quality of life (QOL). Treatments for CRCI are being developed and evaluated. Memory and attention adaptation training (MAAT) is a cognitive-behavioral therapy (CBT) demonstrated to improve CRCI symptoms and QOL in previous research. The aim of this article is to describe a single-case experimental design (SCED) approach to evaluate interventions for CRCI in clinical practice with patient-reported outcome measures (PROs). We illustrate the use of contemporary SCED methods as a means of evaluating MAAT, or any CRCI treatment, once clinically deployed. With the anticipated growth of cancer survivorship and concurrent growth in the number of survivors with CRCI, the treatment implementation and evaluation methods described here can be one way to assess and continually improve CRCI rehabilitative services.

摘要翻译： 

癌症相关认知障碍（CRCI）影响相当比例的癌症幸存者，并对幸存者的功能和生活质量（QOL）产生显著的负面影响。目前，针对CRCI的治疗方法正在研发和评估中。记忆与注意力适应性训练（MAAT）作为一种认知行为疗法（CBT），在先前的研究中已被证实能够改善CRCI症状及提升生活质量。本文旨在阐述一种采用单案例实验设计（SCED）结合患者报告结局指标（PROs）的方法，以评估临床实践中针对CRCI的干预措施。我们展示了如何运用现代SCED方法，对临床实践中已实施的MAAT或任何CRCI治疗方案进行效果评估。随着癌症幸存者数量的预期增长，以及伴有CRCI的幸存者人数同步增加，本文所述的治疗实施与评估方法可作为评估并持续改进CRCI康复服务的一种有效途径。

原文链接：

Using Single-Case Experimental Design and Patient-Reported Outcome Measures to Evaluate the Treatment of Cancer-Related Cognitive Impairment in Clinical Practice