Vital signs are routinely measured in secondary healthcare settings and can be used to detect clinical problems, guide treatment, and monitor response to treatment. Vital signs are less frequently measured in palliative care settings. Reasons for this are unclear. This scoping review aimed to assess the generic use of vital signs in palliative care, and its role in prognostication for adult patients with cancer receiving palliative care. Medline, Embase, and CINAHL were searched for articles involving adult patients with advanced cancer receiving palliative care who had their vital signs measured. Twenty-six articles were identified in which one or a combination of vital signs, with or without other clinical parameters, was used to prognosticate for patients. An additional three articles investigated the generic use of vital signs in patients with advanced cancer. There was significant heterogeneity between identified studies, with some indication that changes in vital signs may indicate that a patient is close to death. However, other studies suggested that patients may maintain normal vital signs until the time of death. Further studies are needed to explore whether abnormal vital signs may be used as a prognostic indicator for patients with cancer receiving palliative care.
生命体征在二级医疗环境中被常规测量,可用于发现临床问题、指导治疗并监测治疗反应。然而在姑息治疗环境中,生命体征的测量频率较低,其原因尚不明确。本范围综述旨在评估生命体征在姑息治疗中的常规应用情况,及其对接受姑息治疗的成年癌症患者预后判断的作用。通过检索Medline、Embase和CINAHL数据库,筛选出涉及接受姑息治疗的晚期成年癌症患者生命体征测量的相关文献。共纳入26篇文献,这些研究采用单一或组合生命体征指标(部分结合其他临床参数)对患者进行预后评估。另有3篇文献探讨了晚期癌症患者生命体征的常规应用情况。现有研究存在显著异质性,部分证据表明生命体征变化可能提示患者临近死亡,但也有研究显示患者可能直至死亡前仍保持正常生命体征。未来需要进一步研究异常生命体征是否可作为接受姑息治疗的癌症患者的预后指标。