Cancer often causes long-term physical and psychological impairments. Lifestyle modification and nature-based interventions (NBIs) can have a positive impact on patients’ quality of life (QOL). This participants-blinded, non-randomized controlled study assessed parameters at weeks 0, 12, and 24, including, as a primary endpoint, QOL in cancer patients on the Functional Assessment of Cancer Therapy—General (FACT-G) at week 12. QOL in breast cancer patients, fatigue, well-being, stress, anxiety/depression, socio-psychological well-being, benefits of nature interaction, insomnia, self-efficacy, mindfulness, and self-compassion were assessed as secondary endpoints. N = 107 cancer patients (96.3% women; 52.5 ± 9.3 years, 80.4% breast cancer) were assigned to either a 12-week nature-based (NDC; n = 56) or conventional (DC; n = 51) oncology day care clinic program, whereby the assignment group was not known to the participants. There was no significant group difference for the primary endpoint. At week 24, QOL, fatigue, mindfulness and self-compassion scores were significantly higher, and at weeks 12 and 24, the insomnia score was significantly lower in NDC compared to DC. In conclusion, this study indicates positive and clinically relevant effects of the program on QOL, fatigue, and psychological parameters. NBIs seem to have a more pronounced effect.
癌症常导致患者长期的身心功能受损。生活方式调整与基于自然的干预措施可对患者生活质量产生积极影响。本研究采用参与者盲法、非随机对照设计，在第0、12、24周评估各项指标，其中主要终点为第12周时采用癌症治疗功能评估量表（FACT-G）测量的癌症患者生活质量。次要终点包括乳腺癌患者生活质量、疲劳程度、幸福感、压力水平、焦虑/抑郁状态、社会心理健康、自然互动的获益程度、失眠状况、自我效能感、正念水平及自我关怀能力。共纳入107例癌症患者（女性占96.3%；平均年龄52.5±9.3岁；乳腺癌患者占80.4%），分别接受为期12周的基于自然的肿瘤日间护理项目（NDC组，n=56）或常规肿瘤日间护理项目（DC组，n=51），分组情况对参与者设盲。主要终点指标未显示显著组间差异。在第24周，NDC组的生活质量、疲劳改善、正念水平及自我关怀评分显著优于DC组；在第12周和第24周，NDC组的失眠评分显著更低。结论表明，该项目对患者生活质量、疲劳程度及心理指标具有积极且具临床意义的改善作用，其中基于自然的干预措施效果更为显著。
肿瘤(癌症)患者之家