Many patients with cancer make use of complementary medicine alongside conventional medicine, but clinicians in oncology often lack the knowledge to adequately advise patients on the evidence base for complementary therapies. This study aims to provide an overview of recently published systematic reviews that assess the effects of complementary therapies on patient-reported health outcomes in patients with cancer. Systematic reviews, including a meta-analysis of at least two randomized controlled trials, were identified from the PubMed, Embase, Cochrane Library, CINAHL and PsycINFO databases. The methodological quality was assessed with AMSTAR 2. One hundred systematic reviews were included. The results suggest that several complementary therapies can improve health outcomes reported by patients with cancer, such as acupuncture to relieve pain, music interventions to reduce anxiety and yoga to improve cancer-related fatigue. The side effects related to complementary therapy use are generally mild. The results remain inconclusive for some intervention–outcome combinations. Many of the included systematic reviews insufficiently assessed the causes and impact of bias in their interpretation of the results. This overview of systematic reviews can support clinicians in counselling their patients on this topic and provide directions for future research and clinical practice guidelines in the field of complementary medicine.
许多癌症患者在常规治疗之外会采用补充医学疗法，但肿瘤临床医生往往缺乏足够知识为患者提供基于证据的补充疗法建议。本研究旨在系统梳理近期发表的评估补充疗法对癌症患者自报健康结局影响的系统综述。通过检索PubMed、Embre、Cochrane Library、CINAHL及PsycINFO数据库，筛选出包含至少两项随机对照试验荟萃分析的系统综述，并采用AMSTAR 2工具评估方法学质量。最终纳入100篇系统综述。研究结果表明，部分补充疗法可改善癌症患者自报的健康结局，例如针灸缓解疼痛、音乐干预减轻焦虑、瑜伽改善癌因性疲乏等。补充疗法相关副作用普遍较轻，但某些干预措施与结局指标的关联性尚未得出明确结论。多数纳入综述在结果解读中对偏倚来源及其影响的评估尚不充分。本系统综述的整合分析可为临床医生提供患者咨询依据，并为补充医学领域的未来研究及临床实践指南制定指明方向。
肿瘤(癌症)患者之家