En bloc resection of bladder tumor (ERBT) is a promising alternative for non-muscle-invasive bladder cancer management. However, the tumor characteristics and surgeon’s experience influence its application. Therefore, in this pilot study, we developed a technique called “rotatable bi-channel en bloc resection of bladder tumor (RBC-ERBT)” and assessed its feasibility, efficacy, and safety compared with those of conventional ERBT. In an ex vivo porcine bladder model, 160 bladder lesions of varying morphologies (exophytic and flat) and sizes (1 and 2 cm) were created and evenly distributed across different locations. A total of 160 procedures were performed, with the ERBT and RBC-ERBT group each exhibiting 80 lesions. RBC-ERBT had a significantly higher technical success rate than ERBT (98.8% vs. 77.5%) for exophytic and flat lesions of both sizes and dome lesions. The procedure time was significantly shorter in the RBC-ERBT group, particularly for flat lesions, lesions with a 2 cm diameter, and lesions located at the dome. RBC-ERBT had a significantly lower piecemeal resection rate than ERBT (0% vs. 18.8%). The incidence of perforation or detrusor muscle sampling did not differ between the groups. Compared with conventional ERBT, RBC-ERBT offered improved success rates, reduced resection times, and effective management of challenging lesions.
膀胱肿瘤整块切除术（ERBT）是治疗非肌层浸润性膀胱癌的一种有前景的替代方法。然而，肿瘤特征和外科医生的经验会影响其应用。因此，在这项初步研究中，我们开发了一种名为“可旋转双通道膀胱肿瘤整块切除术（RBC-ERBT）”的技术，并与传统ERBT比较，评估了其可行性、有效性和安全性。在离体猪膀胱模型中，我们创建了160个不同形态（外生型和扁平型）和大小（1厘米和2厘米）的膀胱病变，并将其均匀分布在不同位置。共进行了160次手术，ERBT组和RBC-ERBT组各包含80个病变。对于两种大小的外生型和扁平型病变以及穹窿部病变，RBC-ERBT的技术成功率显著高于ERBT（98.8%对77.5%）。RBC-ERBT组的手术时间显著缩短，尤其是对于扁平型病变、直径为2厘米的病变以及位于穹窿部的病变。RBC-ERBT的分块切除率显著低于ERBT（0%对18.8%）。两组在穿孔或逼尿肌取样发生率方面没有差异。与传统ERBT相比，RBC-ERBT提供了更高的成功率、更短的手术时间，并能有效处理具有挑战性的病变。
肿瘤(癌症)患者之家