Human papillomavirus (HPV) is a common sexually transmitted infection, with over 40% prevalence in the US. Oropharyngeal cancers (OPCs) driven by high-risk HPV are increasing (up to 90%), with HPV vaccination being the only prevention available. The aim of this study was to investigate HPV vaccination among patients aged between 18 and 26 years old with at least one encounter at a large healthcare system and identify sociodemographic factors associated with vaccine initiation and completion. A cross-sectional retrospective study was conducted between 2018 and 2021, including 265,554 patients identified from the Clinical Data Warehouse. HPV vaccination status by age, sex, race/ethnicity, insurance type, primary care (PCP) visits in the past year, alcohol, tobacco, illicit drug use, and age at vaccination was examined. Overall, 33.6% of females and 25.4% of males have completed the HPV vaccine. Black Americans were 35% more likely to initiate the vaccine than White Americans but were less likely to complete the entire course. Overall, HPV vaccination prevalence was far below the Health People 2030 goal of 80%, especially in young males. This low rate is troubling, since many patients had a PCP visit and remained unvaccinated, which serves as a missed opportunity for vaccination.
人乳头瘤病毒（HPV）是一种常见的性传播感染，在美国的感染率超过40%。由高危型HPV引发的口咽癌（OPCs）发病率持续上升（高达90%），而HPV疫苗接种是目前唯一可用的预防手段。本研究旨在调查某大型医疗系统中18至26岁、至少有过一次就诊记录的患者的HPV疫苗接种情况，并分析与疫苗启动和完成相关的社会人口学因素。研究于2018年至2021年间开展了一项横断面回顾性研究，从临床数据仓库中纳入了265,554名患者。研究按年龄、性别、种族/民族、保险类型、过去一年的初级保健（PCP）就诊情况、酒精使用、烟草使用、非法药物使用以及接种年龄对HPV疫苗接种状况进行了分析。总体而言，33.6%的女性和25.4%的男性完成了HPV疫苗接种。非裔美国人启动疫苗接种的可能性比白人高35%，但完成全程接种的可能性较低。总体来看，HPV疫苗接种率远低于《健康人民2030》设定的80%目标，尤其在年轻男性中接种率偏低。这一低接种率令人担忧，因为许多患者曾进行过初级保健就诊却未接种疫苗，这构成了疫苗接种机会的错失。
肿瘤(癌症)患者之家