For unresectable intrahepatic cholangiocarcinoma (iCC), different locoregional treatments (LRT) could be proposed to patients, including radiofrequency ablation (RFA) and microwave ablation (MWA), external beam radiotherapy (EBRT) or transarterial treatments, depending on patient and tumor characteristics and local expertise. These different techniques of LRT have not been compared in a randomized clinical trial; most of the relevant studies are retrospective and not comparative. The aim of this narrative review is to help clinicians in their everyday practice discuss the pros and cons of each LRT, depending on the individual characteristics of their patients.
对于不可切除的肝内胆管癌(iCC),根据患者及肿瘤特征以及当地医疗条件,可考虑采用不同的局部区域治疗方法(LRT),包括射频消融(RFA)、微波消融(MWA)、外照射放疗(EBRT)或经动脉介入治疗。目前尚未有随机临床试验对这些不同的LRT技术进行比较;大多数相关研究为回顾性且缺乏对照。本叙述性综述旨在帮助临床医生在日常实践中,根据患者个体特征,探讨各种LRT的利弊。
Locoregional Treatment in Intrahepatic Cholangiocarcinoma: Which Treatment for Which Patient?