文章：

胸膜孤立性纤维瘤手术：现有证据综述

Surgery for Solitary Fibrous Tumors of the Pleura: A Review of the Available Evidence

原文发布日期：18 August 2023

DOI: 10.3390/cancers15164166

类型: Article

开放获取: 是

英文摘要：

Solitary fibrous tumors of the pleura (pSFT) are a relatively rare neoplasms that can arise from either visceral or parietal pleura and may have different aggressive biological behaviors. Surgery is well known to be the cornerstone of the treatment for pSFT. We reviewed the existing literature, focusing on the role of surgery in the management and treatment of pSFT. All English-written literature has been reviewed, focusing on those reporting on the perioperative management and postoperative outcomes. Surgery for pSFT is feasible and safe in all experiences reported in the literature, but surgical approaches and techniques may vary according to the tumor dimensions, localization, and surgeons’ skills. Long-term outcomes are good, with a 10-year overall survival rate of more than 70% in most of the reported experiences; on the other hand, recurrence may happen in up to 17% of cases, which occurs mainly in the first two years after surgery, but case reports suggest the need for a longer follow-up to assess the risk of late recurrence. Malignant histology and dimensions are the most recognized risk factors for recurrence. Recurrence might be operated on in select patients. Surgery is the treatment of choice in pSFT, but a radical resection and a careful postoperative follow-up should be carried out.

摘要翻译： 

胸膜孤立性纤维瘤（pSFT）是一种相对罕见的肿瘤，可起源于脏层或壁层胸膜，并可能表现出不同的侵袭性生物学行为。众所周知，手术是治疗pSFT的基石。我们回顾了现有文献，重点关注手术在pSFT管理和治疗中的作用。所有英文文献均被纳入回顾，重点关注围手术期管理和术后结果的报告。文献报道的所有经验均表明，pSFT手术是可行且安全的，但手术入路和技术可能因肿瘤大小、位置和外科医生的技能而异。长期预后良好，大多数报道经验中10年总生存率超过70%；另一方面，复发率可能高达17%，主要发生在术后前两年，但病例报告提示需要更长时间的随访以评估晚期复发风险。恶性组织学类型和肿瘤大小是公认的复发风险因素。对于部分患者，复发后可再次手术。手术是pSFT的首选治疗方法，但应进行根治性切除并实施细致的术后随访。

原文链接：

Surgery for Solitary Fibrous Tumors of the Pleura: A Review of the Available Evidence