文章：

三维打印技术在妇科近距离放射治疗中的应用——叙述性综述

The Use of 3D Printing Technology in Gynaecological Brachytherapy—A Narrative Review

原文发布日期：18 August 2023

DOI: 10.3390/cancers15164165

类型: Article

开放获取: 是

英文摘要：

Radiation therapy, including image-guided adaptive brachytherapy based on magnetic resonance imaging, is the standard of care in locally advanced cervical and vaginal cancer and part of the treatment in other primary and recurrent gynaecological tumours. Tumour control probability increases with dose and brachytherapy is the optimal technique to increase the dose to the target volume while maintaining dose constraints to organs at risk. The use of interstitial needles is now one of the quality indicators for cervical cancer brachytherapy and needles should optimally be used in ≥60% of patients. Commercially available applicators sometimes cannot be used because of anatomical barriers or do not allow adequate target volume coverage due to tumour size or topography. Over the last five to ten years, 3D printing has been increasingly used for manufacturing of customised applicators in brachytherapy, with gynaecological tumours being the most common indication. We present the rationale, techniques and current clinical evidence for the use of 3D-printed applicators in gynaecological brachytherapy.

摘要翻译： 

放射治疗，包括基于磁共振成像的图像引导自适应近距离放射治疗，是局部晚期宫颈癌和阴道癌的标准治疗方案，也是其他原发性和复发性妇科肿瘤治疗的一部分。肿瘤控制概率随剂量增加而提高，而近距离放射治疗是在保持危及器官剂量限制的同时提高靶区剂量的最优技术。目前，组织间插植针的使用已成为宫颈癌近距离放射治疗的质量指标之一，建议至少60%的患者应优化使用插植针。由于解剖结构限制、肿瘤体积或形态学因素，市售施源器有时无法使用或难以实现充分的靶区覆盖。近五至十年来，三维打印技术已越来越多地应用于近距离放射治疗定制施源器的制造，其中妇科肿瘤是最常见的适应症。本文阐述了妇科近距离放射治疗中应用三维打印施源器的理论基础、技术方法及当前临床证据。

原文链接：

The Use of 3D Printing Technology in Gynaecological Brachytherapy—A Narrative Review