文章：

造血干细胞移植与嵌合抗原受体T细胞疗法中的远程医疗应用

Telemedicine in Hematopoietic Cell Transplantation and Chimeric Antigen Receptor-T Cell Therapy

原文发布日期：15 August 2023

DOI: 10.3390/cancers15164108

类型: Article

开放获取: 是

英文摘要：

Telemedicine has played an important role in delivering healthcare for primary care, chronic disease patients, and those with solid organ malignancies. However, its application in subspecialties such as hematologic malignancies, hematopoietic cell transplantation (HCT), or chimeric antigen receptor-T cell (CAR-T) therapy is not widespread since physical examination is a vital component in delivering care. During the COVID-19 pandemic, we widely used telemedicine, since protecting our immunocompromised patients became our top priority. The employment of HCT and CAR-T therapies continues to grow for high-risk hematologic malignancies, particularly in older and frail patients who must visit specialty centers for treatment access. Generally, HCT and CAR-T therapy care is highly complex, necessitating commitment from patients, caregivers, and a multidisciplinary team at specialty academic centers. All healthcare systems adapted to the crisis and implemented rapid changes during the COVID-19 public health emergency (PHE). Telemedicine, a vital modality for delivering healthcare in underserved areas, experienced rapid expansion, regardless of the geographic region, during the COVID-19 PHE. The data emerging from practices implemented during the PHE are propelling the field of telemedicine forward, particularly for specialties with complex medical treatments such as HCT and CAR-T therapy. In this review, we examine the current data on telemedicine in HCT and cellular therapy care models for the acute and long-term care of our patients.

摘要翻译： 

远程医疗在初级保健、慢性病患者及实体器官恶性肿瘤患者的医疗服务中发挥着重要作用。然而，其在血液系统恶性肿瘤、造血细胞移植（HCT）或嵌合抗原受体T细胞（CAR-T）治疗等亚专科领域的应用尚未普及，因为体格检查是提供诊疗服务的重要组成部分。在COVID-19大流行期间，由于保护免疫功能低下患者成为首要任务，我们广泛采用了远程医疗。针对高危血液系统恶性肿瘤，尤其是需要前往专科中心接受治疗的老年体弱患者，HCT和CAR-T疗法的应用持续增长。通常，HCT和CAR-T治疗护理高度复杂，需要患者、照护者及专科学术中心多学科团队的共同投入。在COVID-19突发公共卫生事件期间，所有医疗系统均适应危机并实施了快速变革。远程医疗作为医疗服务不足地区的重要医疗模式，在COVID-19突发公共卫生事件期间实现了跨地域的快速扩展。基于突发公共卫生事件期间实践产生的数据，正在推动远程医疗领域的发展，特别是对于HCT和CAR-T治疗等复杂医疗专科。本综述通过现有数据，探讨远程医疗在HCT及细胞治疗护理模式中对患者急性期与长期照护的应用现状。

原文链接：

Telemedicine in Hematopoietic Cell Transplantation and Chimeric Antigen Receptor-T Cell Therapy