文章：

癌症代谢重编程：连接细胞内应激和癌症行为的桥梁

Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors

原文发布日期：2020-04-30

DOI: 10.1093/nsr/nwaa082

类型: Journal Article

开放获取: 是

英文摘要：

Extensive changes in cellular metabolisms have been observed in cancer. They are probably induced by the same intracellular stressor, persistent off-balance in intracellular pH across possibly all adult cancers. It is these altered metabolisms that gives rise to a variety of cancerous behaviors such as continuous cell division, metastasis and drug resistance.

摘要翻译： 

在癌症中观察到细胞代谢发生了广泛变化。这些变化很可能由同一细胞内应激源引发，即几乎所有成人癌症中都存在的细胞内pH值持续性失衡。正是这些改变的代谢方式导致了各种癌性行为，例如持续的细胞分裂、转移和耐药性。

原文链接：

Metabolic reprogramming in cancer: the bridge that connects intracellular stresses and cancer behaviors