文章：

单克隆丙种球蛋白病的皮肤表现

Cutaneous manifestations of monoclonal gammopathy

原文发布日期：2022-04-11

DOI: 10.1038/s41408-022-00661-1

类型: Review Article

开放获取: 是

英文摘要：

Monoclonal gammopathy associated with dermatological manifestations are a well-recognized complication. These skin disorders can be associated with infiltration and proliferation of a malignant plasma cells or by a deposition of the monoclonal immunoglobulin in a nonmalignant monoclonal gammopathy. These disorders include POEMS syndrome, light chain amyloidosis, Schnitzler syndrome, scleromyxedema and TEMPI syndrome. This article provides a review of clinical manifestations, diagnostics criteria, natural evolution, pathogenesis, and treatment of these cutaneous manifestations.
 

摘要翻译： 

皮肤病与单克隆丙种球蛋白病相关是其公认的并发症。这些皮肤病变可能与恶性浆细胞的浸润增殖有关，也可能由非恶性单克隆丙种球蛋白病中单克隆免疫球蛋白沉积所致。此类疾病包括POEMS综合征、轻链淀粉样变性、施尼茨勒综合征、硬化性黏液水肿以及TEMPI综合征。本文综述了这些皮肤表现的临床表现、诊断标准、自然病程、发病机制及治疗方法。

原文链接：

Cutaneous manifestations of monoclonal gammopathy