文章：

多发性骨髓瘤中的生活方式考量

Lifestyle considerations in multiple myeloma

原文发布日期：2021-10-26

DOI: 10.1038/s41408-021-00560-x

类型: Review Article

开放获取: 是

英文摘要：

As the prognosis for multiple myeloma (MM) has significantly improved and patients remain on therapy longer, there is a need for supportive care interventions to optimize patient quality of life (QOL) and functional status over the course of cancer treatment. MM is characterized by a significant symptom burden and a relatively lower QOL compared to other cancers. This review evaluates the role of healthy lifestyle behaviors in improving both the physical functioning and psychological well-being of the MM population. We (1) describe the current literature on physical activity, weight management, diet, sleep, and substance use in the context of MM, (2) present important considerations for incorporating lifestyle factors into clinical practice, and (3) identify directions for future research. Developing MM-specific guidelines for modifiable lifestyle changes that take into account both the length of treatment and the unique disease features (i.e. osteolytic lesions and anemia) may provide a promising path for improved patient QOL and functioning.
 

摘要翻译： 

随着多发性骨髓瘤（MM）预后显著改善及患者治疗周期延长，在癌症治疗过程中需要通过支持性护理干预来优化患者的生活质量（QOL）和功能状态。与其他癌症相比，MM具有症状负担重、生活质量相对较低的特点。本综述评估了健康生活方式行为对改善MM患者躯体功能及心理健康的作用。我们（1）梳理了当前关于MM患者体力活动、体重管理、饮食、睡眠及物质使用的研究文献，（2）提出将生活方式因素纳入临床实践的重要考量，并（3）指明未来研究方向。制定针对MM的可干预生活方式指南（需综合考虑治疗周期及疾病独特性，如溶骨性病变和贫血），可能为提升患者生活质量与功能状态提供可行路径。

原文链接：

Lifestyle considerations in multiple myeloma