维持治疗在多发性骨髓瘤中的作用
The role of maintenance therapy in multiple myeloma
原文发布日期:2016-10-21
DOI: 10.1038/bcj.2016.89
类型: Review
开放获取: 是
英文摘要:
摘要翻译:
原文链接:
Multiple myeloma is the second most common type of blood cancer and remains incurable despite advances in therapy. Current therapy for multiple myeloma includes a phased-approach, often consisting of initial induction therapy, consolidation and maintenance therapy. With an ever-growing landscape of treatment options, the approach to optimal therapy has become increasingly complex. Specifically, controversy surrounds the optimal use and duration of maintenance therapy. We conducted a comprehensive literature search to analyze the most current literature and to provide recommendations for maintenance therapy in multiple myeloma.
多发性骨髓瘤是第二常见的血液恶性肿瘤,尽管治疗手段不断进步,但目前仍无法治愈。现行多发性骨髓瘤治疗采用阶段性疗法,通常包括初始诱导治疗、巩固治疗和维持治疗。随着治疗方案不断涌现,优化治疗策略变得日益复杂。特别是围绕维持治疗的最佳应用时机和治疗持续时间仍存在争议。我们通过全面文献检索分析了最新研究数据,旨在为多发性骨髓瘤的维持治疗提供临床建议。
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