文章：

不同种族亚群多发性骨髓瘤患者第二原发恶性肿瘤的可变风险

Variable risk of second primary malignancy in multiple myeloma patients of different ethnic subgroups

原文发布日期：2014-09-05

DOI: 10.1038/bcj.2014.63

类型: Original Article

开放获取: 是

英文摘要：

Second primary malignancies (SPMs) among multiple myeloma (MM) patients have been reported with an estimated incidence varying from 1 to 15%. We have previously reported that significant disparity exists in MM survival across patients of different ethnicities. We undertook a Surveillance Epidemiology and End Results-based analysis to describe the incidence of SPMs among MM patients of different ethnicities, to explore the variable impact that SPMs might have on MM outcomes of patients across racial subgroups. We found that the risk of developing SPMs among MM patients is variable depending on the patient’s ethnic background. This warrants further exploration of the impact of SPMs on outcomes of MM patients across different racial subgroups, especially in the form of prospective data collection and analyses.

摘要翻译： 

多发性骨髓瘤（MM）患者中第二原发恶性肿瘤（SPMs）的报道发生率在1%至15%之间。我们先前已报告指出，不同种族患者的MM生存率存在显著差异。我们基于监测流行病学及最终结果数据库进行分析，旨在描述不同种族MM患者中SPMs的发生率，并探讨SPMs可能对各种族亚组MM结局产生的差异性影响。我们发现，MM患者发生SPMs的风险因种族背景而异。这有必要进一步探索SPMs对不同种族亚组MM患者结局的影响，特别是通过前瞻性数据收集与分析的形式进行深入研究。

原文链接：

Variable risk of second primary malignancy in multiple myeloma patients of different ethnic subgroups