文章：

免疫工程学：纳米技术如何增强癌症免疫疗法

Immunoengineering: How Nanotechnology Can Enhance Cancer Immunotherapy

原文发布日期：2015-04-09

DOI: 10.1016/j.cell.2015.03.037

类型: MiniReview

开放获取: 是

英文摘要：

Although cancer immunotherapy can lead to durable outcomes, the percentage of patients who respond to this disruptive approach remains modest to date. Encouragingly, nanotechnology can enhance the efficacy of immunostimulatory small molecules and biologics by altering their co-localization, biodistribution, and release kinetics.

摘要翻译： 

尽管癌症免疫疗法能带来持久疗效，但迄今为止对这种革新性方法产生反应的患者比例仍较为有限。值得庆幸的是，纳米技术能够通过改变免疫刺激小分子和生物制剂的共定位、生物分布及释放动力学特性来增强其疗效。

原文链接：

Immunoengineering: How Nanotechnology Can Enhance Cancer Immunotherapy