文章：

癌症进展和治疗中的遗传相互作用

Genetic Interactions in Cancer Progression and Treatment

原文发布日期：2011-04-01

DOI: 10.1016/j.cell.2011.03.020

类型: Perspective

开放获取: 是

英文摘要：

As cancer cell genomes are unveiled at a breathtaking pace, the genetic principles at play in cancer are emerging in all their complexity, prompting the assessment of classical genetic interaction models. Here, we discuss the implications of these findings for cancer progression and heterogeneity and for the development of new therapeutic approaches.

摘要翻译： 

随着癌细胞基因组以惊人的速度被揭示，癌症中起作用的遗传原理正展现其全部复杂性，这促使我们重新评估经典的基因互作模型。在此，我们将探讨这些发现对癌症进展与异质性以及新治疗方法开发的影响。

原文链接：

Genetic Interactions in Cancer Progression and Treatment